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Article

Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 2009

Ma Yan, Takeuchi Mai, Sugiura Reiko, Sio Susie O, Kuno Takayoshi

Abstract excerpt

Adaptins are subunits of the heterotetrameric (beta/mu/gamma/sigma) adaptor protein (AP) complexes that are involved in clathrin-mediated membrane trafficking. Here, we show that in Schizosaccharomyces pombe the deletion strains of each individual subunit of the AP-1 complex [Apl2 (beta), Apl4 (gamma), Apm1 (mu) and Aps1 (sigma)] caused distinct phenotypes on growth sensitivity to temperature or drugs. We also...

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PMID: 19624755
DOI: 10.1111/j.1365-2443.2009.01327.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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