Article
Generation of a human ovarian granulosa cell model from induced pluripotent stem cells
2022-05-15
Abstract excerpt
<h4>SUMMARY</h4> Sex development is an intricate and crucial process in all vertebrates that ensures the continued propagation of genetic diversity within a species, and ultimately their survival. Perturbations in this process can manifest as variations/differences of sex development (VSD/DSD). Primary gonadal somatic cells – the ovarian granulosa cells (GCs) in the case of women – represent the absolute model to...
Topics
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- Biomedical Ethics and Regulation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Pluripotent Stem Cells Research
- Prenatal Screening and Diagnostics
- Renal and related cancers
- Reproductive Biology and Fertility
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- ffc0b275-23ea-55ab-aaef-d2bd31aa5fba
- DOI
- 10.1101/2022.05.15.491993
