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Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors

14 Aug 2023

Abstract excerpt

Formation of either an ovary or a testis during human embryonic life is one of the most important sex-specific events leading to the emergence of secondary sexual characteristics and sex assignment of babies at birth. Our study focused on the sex-specific and sex-indifferent characteristics of the prenatal ovarian stromal cells, cortical cords, and germline, with the discovery that the ovarian mesenchymal cells...

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PMID: 37582368
DOI: 10.1016/j.devcel.2023.07.014

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