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Article

Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection

2025-12-05

Abstract excerpt

1. <h4>ABSTRACT</h4> Orthoflaviviruses (OFVs) are the primary cause of arboviral disease worldwide, leading to large numbers of hospitalisations, sequelae and deaths associated. Viral genome replication is catalysed by non-structural protein 5 (NS5), the largest and most conserved protein in these viruses. Here, we used quantitative proteomics to identify host cell interactors of Zika virus (ZIKV), Usutu virus (U...

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Literature Corpus work
ffb6722e-cf0d-5ea9-8109-46b3e431bd9b
DOI
10.64898/2025.12.05.692556
Open publication

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Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infectionDOI 10.64898/2025.12.05.692556
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