Article

Nuclear activities and interactome of the NS5 protein of Tick-Borne Encephalitis Virus

2025-11-30

Abstract excerpt

Orthoflaviviruses are RNA viruses responsible for significant diseases in humans, domesticated animals and wildlife. Their NS5 protein is central in viral replication, functioning both as an RNA-dependent RNA polymerase and a methyltransferase, while also modulating cellular processes, including the interferon response. Although viral replication is cytoplasmic, the NS5 protein of several mosquito-borne orthoflavi...

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Identifiers and source

Literature Corpus work: 86dc341d-fd93-52b1-aa9e-7d0354e9cd80
DOI: 10.1101/2025.11.29.691275

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