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Article

<i>Plasmodium falciparum</i> infection of human erythroblasts induces transcriptional changes associated with dyserythropoiesis

2023-04-23

Abstract excerpt

During development down the erythroid lineage, hematopoietic stem cells undergo dramatic changes to cellular morphology and function in response to a complex and tightly regulated program of gene expression. In malaria infection, Plasmodium spp . parasites accumulate in the bone marrow parenchyma, and emerging evidence suggests erythroblastic islands are a protective site for parasite development into gametocytes...

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Literature Corpus work
ff9775a4-4b7f-518e-9d79-0a862edac950
DOI
10.1101/2023.04.23.538003
Open publication

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