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Morphological and Transcriptional Changes in Human Bone Marrow During Natural Plasmodium vivax Malaria Infections

8 Jun 2020

Abstract excerpt

BACKGROUND: The presence of Plasmodium vivax malaria parasites in the human bone marrow (BM) is still controversial. However, recent data from a clinical case and experimental infections in splenectomized nonhuman primates unequivocally demonstrated the presence of parasites in this tissue. METHODS: In the current study, we analyzed BM aspirates of 7 patients during the acute attack and 42 days after drug...

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PMID: 32556188
DOI: 10.1093/infdis/jiaa177

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