Article

Targeting angiogenin as a therapeutic strategy for age-related osteoporosis

2025-11-28

Abstract excerpt

<title>Abstract</title> <p> With aging, the accumulation of cellular stress and cellular senescence drives the progression of osteoporosis. As a conserved cellular stress response, angiogenin (ANG) induces the cleavage of cytoplasmic transfer RNAs (tRNAs) to generate tRNA-derived stress-induced RNAs (tiRNAs) with diverse functional roles in various diseases. However, their biological functions in regulating oste...

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Literature Corpus work: ff8ea65c-e79c-5946-a357-a1357d3c8728
DOI: 10.21203/rs.3.rs-7830644/v1

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