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Article

Insight into the Role of Angiopoietins in Ageing-Associated Diseases

8 Dec 2020

Abstract excerpt

Angiopoietin (Ang) and its receptor, TIE signaling, contribute to the development and maturation of embryonic vasculature as well as vascular remodeling and permeability in adult tissues. Targeting both this signaling pathway and the major pathway with vascular endothelial growth factor (VEGF) is expected to permit clinical applications, especially in antiangiogenic therapies against tumors. Several drugs...

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PMID: 33302426
DOI: 10.3390/cells9122636

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