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Bone Aging, Cellular Senescence, and Osteoporosis

15 Mar 2021

Abstract excerpt

ABSTRACT Changes in aging bone that lead to osteoporosis are mediated at multiple levels, including hormonal alterations, skeletal unloading, and accumulation of senescent cells. This pathological interplay is superimposed upon medical conditions, potentially bone‐wasting medications, modifiable and unmodifiable personal risk factors, and genetic predisposition that accelerate bone loss with aging. In this study,...

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PMID: 33869998
DOI: 10.1002/jbm4.10488

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