Article

Effect of SGLT2 Inhibitors on CKD Progression and All-Cause Mortality: A Meta-Analysis of Randomized Controlled Trials

2025-08-11

Abstract excerpt

<h4>Background: </h4> Sodium-glucose cotransporter 2 (SGLT2) inhibitors have emerged as promising agents for slowing chronic kidney disease (CKD) progression. While individual trials demonstrate renal and survival benefits, questions remain regarding the consistency, generalizability, and magnitude of these effects, particularly across populations with and without diabetes, and amid heterogeneous outcome definitio...

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Literature Corpus work: ff7b9ff2-7f12-5ce5-ab9b-b96ba7c3c574
DOI: 10.1101/2025.08.07.25333212

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