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Cardiorenal outcomes of tirzepatide versus semaglutide in adults with type 2 diabetes and chronic kidney disease: a target trial emulation in the TriNetX Global Collaborative Network

2026-06-21

Abstract excerpt

<title>Abstract</title> <p>Patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) carry the highest absolute cardiorenal risk, yet head-to-head real-world comparisons of tirzepatide and semaglutide in this population are lacking. Using the TriNetX Global Collaborative Network, we emulated a pragmatic randomised trial in adults aged 18–80 years with T2DM (ICD-10 E11.x, ≥ 2 encounters, HbA1c...

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Literature Corpus work
22d6be64-1c46-5420-adf9-e053872b1a2d
DOI
10.21203/rs.3.rs-9573853/v1
Open publication

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Cardiorenal outcomes of tirzepatide versus semaglutide in adults with type 2 diabetes and chronic kidney disease: a target trial emulation in the TriNetX Global Collaborative NetworkDOI 10.21203/rs.3.rs-9573853/v1
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