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Article

VarSAn: associating pathways with a set of genomic variants using network analysis.

Nucleic acids research - 7 Sept 2021

Xie Xiaoman, Kendzior Matthew C, Ge Xiyu, Mainzer Liudmila S, Sinha Saurabh

Abstract excerpt

There is a pressing need today to mechanistically interpret sets of genomic variants associated with diseases. Here we present a tool called 'VarSAn' that uses a network analysis algorithm to identify pathways relevant to a given set of variants. VarSAn analyzes a configurable network whose nodes represent variants, genes and pathways, using a Random Walk with Restarts algorithm to rank pathways for relevance to...

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Identifiers

PMID: 34313777
DOI: 10.1093/nar/gkab624
PMCID: PMC8421213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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