Article
The IGVF catalog-from genetic variation to function.
Nucleic acids research - 6 Jan 2026
Li Daofeng, Liu Shane, Assis Pedro R, Li Mingjie, Dong Shengcheng, Whaling Ian, Jolanki Otto, Kagda Meenakshi, Zhang Wenjin, Macias-Velasco Juan F, Liu Tianjie, Cody Sarah, Antonacci-Fulton Lucinda, Huang Yuanhao, Liu Jie, Montgomery Michael T, Zeiberg Daniel, Jain Shantanu, Pejaver Vikas, Bergquist Timothy, Chen Yile, Radivojac Predrag, Gersbach Charles A, Sherpa Rintsen N, Castro Christopher P, Boyle Alan P, Starita Lea M, Fowler Douglas M, Ahituv Nadav, Dey Kushal K, Majoros William H, Reddy Timothy E, Craven Mark, Sinha Riya, Sverchkov Yuriy, Cai Xiangmeng, Nzima Mpathi Z, Calderwood Michael A, Rozowsky Joel, Gerstein Mark, Ma Jian, Yue Feng, Cherry J Michael, Love Michael I, Engreitz Jesse M, Hitz Benjamin C, Wang Ting
Abstract excerpt
Genomic variation between individuals is essential for understanding how differences in the genome sequence affect molecular and cellular processes. The Impact of Genomic Variation on Function (IGVF) Consortium aims to uncover the relationships among genomic variation, genome function, and phenotypes by combining experimental techniques, such as single-cell mapping and genomic perturbation assays, with...
Topics
- Genetic Variation
- Humans
- Databases, Genetic
- Genomics
- Software
- Phenotype
- Quantitative Trait Loci