Article
Hesperetin Inhibits Xanthine Oxidase Activity via Altering the Protein’s Secondary Structure and Suppressing Superoxide Anion Generation
2024-04-25
Abstract excerpt
Hyperuricemia is mainly caused by the overproduction of uric acid (UA) catalyzed from xanthine by xanthine oxidase (XO) in abnormal purine metabolism in human body. There is an increasing demand for developing novel XO inhibitors of plant origins. The inhibition kinetics and type as well as actions of hesperetin against XO were investigated in vitro using multi-spectroscopic methods including UV-Vis absorption, Fo...
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Identifiers and source
- Literature Corpus work
- ff5f9f3a-ae74-5068-aebe-4b26416cecef
- DOI
- 10.20944/preprints202404.1678.v1
