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Article

Functional characterization of human xanthine oxidase allelic variants.

Pharmacogenetics and genomics - 1 Mar 2008

Kudo Mutsumi, Moteki Toshiko, Sasaki Takamitsu, Konno Yumiko, Ujiie Shuta, Onose Akemi, Mizugaki Michinao, Ishikawa Masaaki, Hiratsuka Masahiro

Abstract excerpt

OBJECTIVE: Xanthine oxidase (XO) catalyzes the oxidation of endogenous and exogenous purines and pyrimidines. In this study, we speculated that individual variations in XO activity are caused by genetic variations in the XO gene. METHODS: To investigate the genetic variations in XO in 96 Japanese participants, denaturing high-performance liquid chromatography was used. To assess the effects of these variations on...

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PMID: 18300946
DOI: 10.1097/FPC.0b013e3282f55e2e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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