Article

From neural border to migratory stage: A comprehensive single cell roadmap of the timing and regulatory logic driving cranial and vagal neural crest emergence

2022-03-23

Abstract excerpt

Neural crest cells exemplify cellular diversification from a multipotent progenitor population. However, the full sequence of molecular choices orchestrating the emergence of neural crest heterogeneity from the embryonic ectoderm remains elusive. Gene-regulatory-networks (GRN) govern early development and cell specification towards definitive neural crest. Here, we combine ultra-dense single cell transcriptomes wi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ff29ddb3-cb1b-5ca7-8f4e-9210c844e815
DOI: 10.1101/2022.03.23.485460

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

From neural border to migratory stage: A comprehensive single cell roadmap of the timing and regulatory logic driving cranial and vagal neural crest emergenceDOI 10.1101/2022.03.23.485460Read

Single-cell transcriptomic landscape of cardiac neural crest cell derivatives during embryonic and neonatal developmentSemantic proximity Read

Genomic mosaicism reveals developmental organization of trunk neural crest-derived gangliaSemantic proximity Read

Human neural crest cells display molecular and phenotypic hallmarks of stem cells.Semantic proximity Read

Neuroblastoma plasticity during metastatic progression stems from the dynamics of an early sympathetic transcriptomic trajectorySemantic proximity Read

Transcriptome profiling of the cardiac neural crest reveals a critical role for MafBSemantic proximity Read

The neural crest: Basic biology and clinical relationships in the craniofacial and enteric nervous systemsSemantic proximity Read

Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcodingSemantic proximity Read

The single-cell and spatial transcriptional landscape of human gastrulation and early brain developmentSemantic proximity Read

Pre-Border Gene Foxb1 Regulates the Differentiation Timing and Autonomic Neuronal Potential of Human Neural Crest CellsSemantic proximity Read

Unraveling the Enigmatic Origin of Neuroblastoma.Semantic proximity Read

Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neuronsSemantic proximity Read

New insights empowered by single-cell sequencing: From neural crest to enteric nervous systemSemantic proximity Read