Article

HIV-1 subtype-specific drug resistance on dolutegravir-based antiretroviral therapy: protocol for a multicentre longitudinal study (DTG RESIST)

2024-05-24

Abstract excerpt

<h4>Introduction</h4> HIV drug resistance poses a challenge to the United Nation’s goal of ending the HIV/AIDS epidemic. The integrase strand transfer inhibitor (InSTI) dolutegravir, which has a higher resistance barrier, was endorsed by the World Health Organization in 2019 for first-, second-, and third-line antiretroviral therapy (ART). This multiplicity of roles of dolutegravir in ART may facilitate the emerge...

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Literature Corpus work: ff097043-ea57-5436-9be1-a8a13701508a
DOI: 10.1101/2024.05.23.24307850

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