Article
A Comprehensive Literature Review of Treatment-Emergent Integrase Resistance with Dolutegravir-Based Regimens in Real-World Settings.
Viruses - 14 Dec 2023
Henegar Cassidy, Letang Emilio, Wang Ruolan, Hicks Charles, Fox Dainielle, Jones Bryn, de Ruiter Annemiek, Vannappagari Vani
Abstract excerpt
After a decade of dolutegravir (DTG) use in various antiretroviral therapy combinations and in diverse populations globally, it is critical to identify HIV strains with reduced drug susceptibility and monitor emergent resistance in people living with HIV who experience virologic failure while on DTG-based regimens. We searched the PubMed, Embase, and Cochrane databases to identify studies that reported DTG...
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