Article

Bcl-2-associated Transcription Factor 1 Phosphorylation Mediated DNA Damage Response in Gastric Cancer

2021-04-20

Abstract excerpt

<h4>Background: </h4> DNA damage response plays critical roles in tumor pathogenesis and radiotherapy resistance. Various cellular activities including the initiation and major steps DNA damage response are regulated by protein phosphorylation, whereas the molecular mechanism remains largely unknown. <h4>Methods: </h4>: A quick label-free phosphoproteomics using high-resolution mass spectrometry and an open search...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fedaf6c4-3b8a-571b-a266-26d64cc4f5a0
DOI: 10.21203/rs.3.rs-431350/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bcl-2-associated Transcription Factor 1 Phosphorylation Mediated DNA Damage Response in Gastric CancerDOI 10.21203/rs.3.rs-431350/v1Read

AURKB is a key to connect oxidative phosphorylation and immune microenvironment in Gastric Cancer.Semantic proximity Read

Histone Phosphorylation in DNA Damage ResponseSemantic proximity Read

Histone Phosphorylation in DNA Damage ResponseSemantic proximity Read

The phosphoproteomic landscape of the DNA damage responseSemantic proximity Read

H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer TherapySemantic proximity Read

Elevated ASF1B Promotes Apoptosis in Gastric Tumour Cells Through the Bax/Bcl-2-p53 Pathway and is Related to a Good PrognosisSemantic proximity Read

Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response RegulatorsSemantic proximity Read

Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in CancersSemantic proximity Read

Mining the tumor phosphoproteome for cancer markers.Semantic proximity Read

Phosphoproteomic subtyping of gastric cancer reveals dynamic transformation with chemotherapy and guides targeted cancer treatmentSemantic proximity Read

Phosphoproteomics Profiling of Human Skin Fibroblast Cells Reveals Pathways and Proteins Affected by Low Doses of Ionizing RadiationSemantic proximity Read

ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage.Semantic proximity Read