Article

Elevated ASF1B Promotes Apoptosis in Gastric Tumour Cells Through the Bax/Bcl-2-p53 Pathway and is Related to a Good Prognosis

2021-09-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Previous studies have shown that ASF1B, a H3-H4 histone chaperone, plays a key role in cancer. However, the prognostic relevance and mechanism of ASF1B in patients with gastric cancer (GC) are not clear. Therefore, we explored the prognostic role of ASF1B in gastric cancer and explored its biological function.<bold>Methods</bold>: From the bioinformatics perspec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bd61f9cb-b254-57b7-8c89-bae81fdf6e52
DOI: 10.21203/rs.3.rs-929676/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Elevated ASF1B Promotes Apoptosis in Gastric Tumour Cells Through the Bax/Bcl-2-p53 Pathway and is Related to a Good PrognosisDOI 10.21203/rs.3.rs-929676/v1Read

Comprehensive Analysis of the Prognostic Value of ITGB Superfamily Members in Gastric Cancer Using Bioinformatics AnalysisSemantic proximity Read

AFAP1L1 is indicative for a grim prognosis and immune microenvironment in gastric cancerSemantic proximity Read

Immune Implication of ASF1B Gene in Hepatocellular CarcinomaSemantic proximity Read

Identification of Function Genes regulating Gastric Cancer progression using Integrated Bioinformatics AnalysisSemantic proximity Read

Expression and prognostic value of E2F family members in gastric cancerSemantic proximity Read

ASF1B Serves as a Potential Therapeutic Target by Influencing Cell Cycle and Proliferation in Hepatocellular CarcinomaSemantic proximity Read

Comprehensive analysis of pan‐cancer reveals potential of ASF1B as a prognostic and immunological biomarkerSemantic proximity Read

ITRAQ-based Bioinformatics Analysis Reveals the Potential Anticancer Effects of ATP4B in Gastric CancerSemantic proximity Read

UBR1 is a prognostic biomarker and therapeutic target associated with immune cell infiltration in gastric cancerSemantic proximity Read

The roles of E2Fs in gastric cancer: the transcription factors E2F1/2/3/4/5 as potential therapeutic targets and E2F6/7/8 as new prognostic biomarkers in gastric cancerSemantic proximity Read

Early B-cell factors involve in the tumorigenesis and predict the overall survival of gastric cancerSemantic proximity Read

PAFAH1B3 Expression Is Correlated With Gastric Cancer Cell Proliferation and Immune InfiltrationSemantic proximity Read