Article

Pan-cancer analysis reveals potential for synergy between SERPINA1 molecular targeting and macrophage-related immunotherapy

2022-09-22

Abstract excerpt

<h4>Background: </h4> The immune response can be modulated by autophagy to alter tumor growth. SERPINA1 is not only an autophagy-related protein but also a serine protease inhibitor with the potential for immunotherapy and targeted drug therapy. Methods Based on the latest multi-omic databases, we evaluated SERPINA1 mRNA and protein expression levels, prognostic value, methylation and mutation, signaling pathway,...

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Literature Corpus work: feb56e89-26ae-59ae-aff3-593e8f27fdfb
DOI: 10.21203/rs.3.rs-2072682/v1

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