Article

Gene co-expression analyses of health(span) across multiple species

2021-04-10

Abstract excerpt

Health(span)-related gene clusters/modules were recently identified based on knowledge about the cross-species genetic basis of health, to interpret transcriptomic datasets describing health-related interventions. However, the cross-species comparison of health-related observations reveals a lot of heterogeneity, not least due to widely varying health(span) definitions and study designs, posing a challenge for the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fea6b7fb-7500-58fb-b2b0-2856eea724f7
DOI: 10.1101/2021.04.08.439030

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gene co-expression analyses of health(span) across multiple speciesDOI 10.1101/2021.04.08.439030Read

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases.Semantic proximity Read

A network-based atlas of human skeletal muscle agingSemantic proximity Read

Identification of common regulators of genes in co-expression networks affecting muscle and meat properties.Semantic proximity Read

MyoScore: a Genetically Anchored Transcriptomic Scoring System for Quantifying Human Skeletal Muscle HealthSemantic proximity Read

Cross-species gene modules emerge from a systems biology approach to osteoarthritisSemantic proximity Read

GWENA: Gene Co-expression Networks Analysis and Extended Modules Characterization in a Single Bioconductor PackageSemantic proximity Read

Elucidating the molecular landscape of centronuclear myopathies in mouse models: an integrative multi-omics and network analysisSemantic proximity Read

Ageing Transcriptome Meta-Analysis Reveals Similarities Between Key Mammalian TissuesSemantic proximity Read

Meta-analysis of inter-species liver co-expression networks elucidates traits associated with common human diseases.Semantic proximity Read

The extracellular matrix phenome across speciesSemantic proximity Read

Phenotypic connections in surprising places.Semantic proximity Read

Transcriptome features of striated muscle aging and predictability of protein level changesSemantic proximity Read