Article
Tumor-Infiltrating B- and T-Cell Repertoire in Pancreatic Cancer Associated With Host and Tumor Features.
Frontiers in immunology - 1 Jan 2021
Pineda Silvia, López de Maturana Evangelina, Yu Katharine, Ravoor Akshay, Wood Inés, Malats Núria, Sirota Marina
Abstract excerpt
Background: Infiltrating B and T cells have been observed in several tumor tissues, including pancreatic ductal adenocarcinoma (PDAC). The majority known PDAC risk factors point to a chronic inflammatory process leading to different forms of immunological infiltration. Understanding pancreatic tumor infiltration may lead to improved knowledge of this devastating disease. Methods: We extracted the immunoglobulins...
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