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The blood metabolome of cognitive function and brain health in middle-aged adults – influences of genes, gut microbiome, and exposome

2024-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Increasing evidence suggests the involvement of metabolic alterations in neurological disorders, including Alzheimer’s disease (AD), and highlights the significance of the peripheral metabolome, influenced by genetic factors and modifiable environmental exposures, for brain health. In this study, we examined 1,387 metabolites in plasma samples from 1,082 dementia-free middle-aged participants of...

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Literature Corpus work
fe9afd04-0f1b-58a8-af5f-841f1919ea2e
DOI
10.1101/2024.12.16.24317793
Open publication

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