Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated analysis of gut metabolome, microbiome, and brain function reveal the role of gut-brain axis in longevity

28 Mar 2024

Abstract excerpt

The role of microbiota-gut-brain axis in modulating longevity remains undetermined. Here, we performed a multiomics analysis of gut metagenomics, gut metabolomics, and brain functional near-infrared spectroscopy (fNIRS) in a cohort of 164 participants, including 83 nonagenarians (NAs) and 81 non-nonagenarians (NNAs) matched with their spouses and offspring. We found that 438 metabolites were significantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet and metabolism studies
Share to Gut microbiota and health
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38548676
DOI: 10.1080/19490976.2024.2331434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated analysis of gut metabolome, microbiome, and brain function reveal the role of gut-brain axis in longevityPMID 38548676Read ↗

Ketogenic Diet Modulates Gut Microbiota-Brain Metabolite Axis in a Sex- and Genotype-Specific Manner in APOE4 Mice.Semantic proximity Read ↗

Impact of dietary fiber on gut microbiota composition, function and gut-brain-modules in healthy adults – a systematic review protocolSemantic proximity Read ↗

Intermittent fasting mitigates cognitive deficits in Alzheimer’s disease via the gut-brain axisSemantic proximity Read ↗

The contribution of age-related changes in the gut-brain axis to neurological disordersSemantic proximity Read ↗

Gut microbiome‐derived metabolites in Alzheimer's disease: Regulation of immunity and potential for therapeuticsSemantic proximity Read ↗

Multi-omics analysis reveals neuroinflammation, activated glial signaling, and dysregulated synaptic signaling and metabolism in the hippocampus of aged miceSemantic proximity Read ↗

Gut–Brain Axis and Neurodegeneration: State-of-the-Art of Meta-Omics Sciences for Microbiota CharacterizationSemantic proximity Read ↗

The interplay between the gut-brain axis and the microbiome: A perspective on psychiatric and neurodegenerative disordersSemantic proximity Read ↗

The blood metabolome of cognitive function and brain health in middle-aged adults – influences of genes, gut microbiome, and exposomeSemantic proximity Read ↗

Microbiome functional gene pathways predict cognitive performance in older adults with Alzheimer’s diseaseSemantic proximity Read ↗

Gut Instinct Redefined: A Comprehensive Review of the Gut Microbiome’s Role in Brain Function, Disease, and Potential TherapiesSemantic proximity Read ↗

Towards understanding brain-gut-microbiome connections in Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.