Article

Introduced chemokine gradients guide transplanted and regenerated retinal neurons toward their natural position in the retina

2022-10-01

Abstract excerpt

Ongoing cell replacement studies and clinical trials have demonstrated the need to control donor and newborn cell behavior within their target tissue. Here we present a methodology to guide stem cell-derived and endogenously regenerated neurons by engineering the microenvironment. Being an “approachable part of the brain,” the eye provides a unique opportunity to study donor neuron fate, migration, and integration...

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Literature Corpus work: fe5e4b34-835b-5b5c-8cd7-6bd404abb7e3
DOI: 10.1101/2022.09.29.510158

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