Article

Dysmorphic neuron density underlies intrinsic epileptogenicity of the centre of cortical tubers

2019-04-29

Abstract excerpt

Cortical tubers are benign lesions that develop in patients with tuberous sclerosis complex (TSC), often resulting in drug-resistant epilepsy. Surgical resection may be required for seizure control, but the extent of the resection required is unclear. Many centres include resection of perituberal cortex, which may be associated with neurological deficits. Also, patients with tubers in eloquent cortex may be exclud...

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Literature Corpus work: fe506c07-ba34-5d84-b1c3-bb9da07307b9
DOI: 10.1101/621607

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