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Article

Cytoarchitectural alterations are widespread in cerebral cortex in tuberous sclerosis complex.

Acta neuropathologica - 1 May 2012

Marcotte Leah, Aronica Eleonora, Baybis Marianna, Crino Peter B

Abstract excerpt

Tubers are cerebral cortical developmental malformations associated with epilepsy and autism in tuberous sclerosis complex (TSC). The disparity between tuber number and severity of neurological impairment often observed in TSC led us to hypothesize that microscopic structural abnormalities distinct from tubers may occur in TSC. Serial frontal to occipital lobe sections were prepared from five postmortem TSC brain...

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Source

Identifiers

PMID: 22327361
DOI: 10.1007/s00401-012-0950-3

Genes

TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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