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Longitudinal Live Imaging Derived 4D Hemodynamics and Dynamic Tissue Mechanics Across Outflow Tract Morphogenesis

2025-08-30

Abstract excerpt

Growth and remodeling of the cardiac outflow tract (OFT) is poorly understood but associated with serious congenital heart defects (CHD). While only a minority of CHDs have identifiable genetic causes, the functional roles of mechanical forces in OFT remodeling are far less characterized. A key barrier has been the lack of longitudinal investigations examining the interplay between dynamic blood flow and wall moti...

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Literature Corpus work
fe4c8f41-d237-51c0-8df2-63c121f3ab1e
DOI
10.1101/2025.08.26.672464
Open publication

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Longitudinal Live Imaging Derived 4D Hemodynamics and Dynamic Tissue Mechanics Across Outflow Tract MorphogenesisDOI 10.1101/2025.08.26.672464
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