Article

Molecular mechanisms of myopathies

2012-01-01

Abstract excerpt

This study was aimed at the investigation of the mechanisms by which mutations on proteins of the thin filaments could lead to cardiac and skeletal muscle diseases. The contractile properties of reconstituted thin filaments were assessed using the quantitative in vitro motility assay. The cardiac disease investigated was the dilated cardiomyopathy (DCM). Pilot work on 2 mutants indicated that, contrarily to what w...

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Identifiers and source

Literature Corpus work: fe3b9687-4c53-5750-b6f4-806633fbe14a
DOI: 10.25560/9917

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