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Influence of Genetic Polymorphisms in P2Y12 Receptor Signaling Pathway on Antiplatelet Response to Clopidogrel in Coronary Heart Disease

2021-10-27

Abstract excerpt

<h4>Backgrounds: </h4>: Remarkable interindividual variability in clopidogrel response is observed, genetic polymorphisms in P2RY12 and its signal pathway is supposed to affect clopidogrel response in CHD patients. <h4>Methods:</h4> 539 CHD patients treated with clopidogrel were recruited. The platelet reaction index (PRI) indicated by VASP-P level were detected in 12-24h after clopidogrel loading dose (LD) or wit...

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Literature Corpus work
fe339056-a340-5656-a1d6-fde4a9ee97a8
DOI
10.21203/rs.3.rs-982213/v1
Open publication

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