Article

Evaluation of mitochondrial DNA copy number estimation techniques

2019-04-16

Abstract excerpt

Mitochondrial DNA copy number (mtDNA-CN), a measure of the number of mitochondrial genomes per cell, is a minimally invasive proxy measure for mitochondrial function and has been associated with several aging-related diseases. Although quantitative real-time PCR (qPCR) is the current gold standard method for measuring mtDNA-CN, mtDNA-CN can also be measured from genotyping microarray probe intensities and DNA sequ...

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Literature Corpus work: fdf86aea-a70b-52ad-8268-8dd037566775
DOI: 10.1101/610238

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