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Birth of new protein folds and functions in the virome

2024-01-23

Abstract excerpt

<h4>Summary</h4> Rapid virus evolution generates proteins essential to infectivity and replication but with unknown function due to extreme sequence divergence 1 . Using a database of 67,715 newly predicted protein structures from 4,463 eukaryotic viral species, we found that 62% of viral proteins are evolutionarily young and lack homologs in the Alphafold database 2,3 . Among the 38% of more ancient viral prot...

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Literature Corpus work
fdf43f72-fcec-5eab-b4f4-94103ec4b9dd
DOI
10.1101/2024.01.22.576744
Open publication

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Birth of new protein folds and functions in the viromeDOI 10.1101/2024.01.22.576744
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