Article

Exosome-like biogenesis from the Golgi releases extracellular vesicles lacking conventional tetraspanins that mediate immune evasion in cancer

2026-05-13

Abstract excerpt

Immunotherapy has improved survival across multiple malignancies but remains largely ineffective in solid cancers such as lung, breast, and pancreatic cancer. A key driver of resistance is the immunosuppressive tumor microenvironment (TME). Although numerous mediators of TME immunosuppression have been identified, therapeutic targeting has provided limited clinical benefit. Tumor-derived extracellular vesicles (EV...

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Literature Corpus work: fdebaa2c-e6ab-5c6b-ad87-74abecb2dc63
DOI: 10.64898/2026.05.13.719612

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