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Article

Extra-cellular vesicles carry proteome of cancer hallmarks

5 Oct 2019

Abstract excerpt

Through lateral transfer, extra-cellular vesicles (EVs) transport their DNA, miRNA, mRNA and proteins such as enzymes mediating drug resistance, transporters as well as growth factors to neighboring cells. By virtue of this horizontal transfer, EVs potentially regulate cell growth, migration, angiogenesis and metastasis and increase tissue permeability in cancer. Furthermore, EVs regulate immune factors and allow...

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PMID: 31585894
DOI: 10.2741/4811

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