Article

Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD

2021-02-02

Abstract excerpt

Psychoactive drugs can transiently perturb brain physiology while preserving brain structure. The role of physiological state in shaping neural function can therefore be investigated through neuroimaging of pharmacologically-induced effects. This paradigm has revealed that neural and experiential effects of lysergic acid diethylamide (LSD) are attributable to its agonist activity at the serotonin-2A receptor. Here...

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Literature Corpus work: 126614ab-d1fc-542a-bce6-957c986d0bc4
DOI: 10.1101/2021.01.31.429016

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