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LSD and psilocybin flatten the brain’s energy landscape: insights from receptor-informed network control theory

2021-05-17

Abstract excerpt

Psychedelics like lysergic acid diethylamide (LSD) and psilocybin offer a powerful window into the function of the human brain and mind, by temporarily altering subjective experience through their neurochemical effects. A recent model postulates that serotonin 2a (5-HT2a) receptor agonism allows the brain to explore its dynamic landscape more readily, as reflected by more diverse (entropic) brain activity. We post...

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Literature Corpus work
cd9da75b-bff1-5f46-ab6e-bc383d9f6356
DOI
10.1101/2021.05.14.444193
Open publication

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LSD and psilocybin flatten the brain’s energy landscape: insights from receptor-informed network control theoryDOI 10.1101/2021.05.14.444193
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