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Modelling metastasis in zebrafish unveils regulatory interactions of cancer-associated fibroblasts with circulating tumour cells

2022-12-11

Abstract excerpt

The dynamic intercommunication between tumour cells and cells from the microenvironment, such as cancer-associated fibroblast (CAFs), is a key factor driving breast cancer (BC) metastasis. Clusters of circulating tumour cells (CTCs), known to bare a higher efficiency at establishing metastases, are found in the blood of BC patients, often accompanied by CAFs in heterotypic CTC-clusters. Previously we have shown th...

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Literature Corpus work
fdd6fd34-c7c6-5c2b-808d-0f2fa54a7b66
DOI
10.1101/2022.12.07.519426
Open publication

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Modelling metastasis in zebrafish unveils regulatory interactions of cancer-associated fibroblasts with circulating tumour cellsDOI 10.1101/2022.12.07.519426
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