Article

Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid

2021-10-20

Abstract excerpt

<h4>Background: </h4> Rapid asexual replication of blood stage malaria parasites is responsible for the severity of disease symptoms and fuels the production of transmission forms. Here, we demonstrate that a Plasmodium chabaudi’s schedule for asexual replication can be orchestrated by isoleucine, a metabolite provided to the parasite in a periodic manner due to the host’s rhythmic intake of food. <h4>Methods:...

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Literature Corpus work: fdadebd6-03be-5202-a552-2f8ec7d5ea8d
DOI: 10.12688/wellcomeopenres.16894.2

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