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Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum development

10 Dec 2019

Abstract excerpt

The blood-feeding behavior of Anopheles females delivers essential nutrients for egg development and drives parasite transmission between humans. Plasmodium growth is adapted to the vector reproductive cycle, but how changes in the reproductive cycle impact parasite development remains unclear. Here, we show that the bloodmeal-induced miR-276-5p fine-tunes the expression of branched-chain amino acid transferase...

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PMID: 31822677
DOI: 10.1038/s41467-019-13627-y

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