Article

Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid

2020-08-24

Abstract excerpt

Rapid asexual replication of blood stage malaria parasites is responsible for the severity of disease symptoms and fuels the production of transmission forms. That malaria parasite species coordinate their cycles of asexual replication with daily rhythms of their host was discovered in the Hippocratic era, but how and why this occurs is enigmatic. Here, we demonstrate that the Plasmodium chabaudi’s schedule for a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5584f013-de16-5a37-a24c-2f87bbeadb74
DOI: 10.1101/2020.08.24.264689

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acidDOI 10.1101/2020.08.24.264689Read

Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acidSemantic proximity Read

Metabolic balancing by miR-276 shapes the mosquito reproductive cycle and Plasmodium falciparum developmentSemantic proximity Read

Linking nutrient sensing and gene expression in Plasmodium falciparum blood‐stage parasitesSemantic proximity Read

Eating at the Table of Another: Metabolomics of Host-Parasite InteractionsSemantic proximity Read

Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state.Semantic proximity Read

Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythmsSemantic proximity Read

Effects of host blood meal source on reproductive output, nutrient reserves and gut microbiome of West Nile virus vector Culex quinquefasciatusSemantic proximity Read

The flexibility of Apicomplexa parasites in lipid metabolismSemantic proximity Read

Virulence is associated with daily rhythms in the within-host replication of the malaria parasite <i>Plasmodium chabaudi</i>Semantic proximity Read

Supply and demand—heme synthesis, salvage and utilization by ApicomplexaSemantic proximity Read

Daily rhythms in the transcriptomes of the human parasite <i>Schistosoma mansoni</i>Semantic proximity Read

Disruption of the coordination between host circadian rhythms and malaria parasite development alters the duration of the intraerythrocytic cycleSemantic proximity Read