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Article

Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction

2020-05-27

Abstract excerpt

Microphysiological systems (MPSs) mimicking human organ function in vitro are an emerging alternative to conventional cell culture and animal models for drug development. Human induced pluripotent stem cells (hiPSCs) have the potential to capture the diversity of human genetics and provide an unlimited supply of cells. Combining hiPSCs with microfluidics technology in MPSs offers new perspectives for drug develop...

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Literature Corpus work
fcc42b61-5ed8-52e9-85e1-910e1a9b90ad
DOI
10.1101/2020.05.24.112771
Open publication

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Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interactionDOI 10.1101/2020.05.24.112771
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