Article

Dysregulation of “Don’t Eat Me” Signaling–Related Genes in Sepsis: A Targeted Transcriptomic Analysis

2026-02-26

Abstract excerpt

Sepsis remains a life-threatening condition with limited therapeutic options targeting immune dysregulation. The CD47-SIRPα “don’t eat me” signaling axis, well characterized in tumor immune evasion, has not been systematically investigated in the context of sepsis. In this study, we performed a targeted transcriptomic analysis of phagocytosis- and “don’t eat me” –related genes using the GSE228541 dataset (14 sepsi...

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Literature Corpus work: fcbf6e19-b30c-552a-9011-b4127b711dea
DOI: 10.64898/2026.02.25.707968

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