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Revealing novel pyroptosis-related therapeutic targets for sepsis based on machine learning

10 Feb 2023

Abstract excerpt

BACKGROUND: Sepsis is one of the most lethal diseases worldwide. Pyroptosis is a unique form of cell death, and the mechanism of interaction with sepsis is not yet clear. The aim of this study was to uncover pyroptosis genes associated with sepsis and to provide early therapeutic targets for the treatment of sepsis. METHODS: Based on the GSE134347 dataset, sepsis-related genes were mined by differential...

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PMID: 36765335
DOI: 10.1186/s12920-023-01453-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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