Article

NSP4 as Adjuvant for Immunogenicity and Design of Effective Therapeutic HPV16 E6/E7/L1 DNA Vaccine in Tumoric and Healthy C57BL/6 Mice

2021-12-23

Abstract excerpt

<h4>Introduction: </h4> In humans, approximately 5% of all cancers are attributable to HPV infection. Prophylactic vaccines can inhibit viral migration and persistence. However, requirement to develop therapeutic treatments prevails. To achieve this goal, we designed a therapeutic HPV DNA vaccine encoding a construct of E6/E7/L1 and used NSP4 antigen as adjuvant to assess efficiency of this construct in generating...

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Literature Corpus work: 9a41b91a-e653-54ec-b4f6-33660bafc001
DOI: 10.21203/rs.3.rs-1176705/v1

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