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Article

Stepwise Enhancement of HPV16 E6/E7 mRNA Vaccine Efficacy Using HSV-1 gD Epitope Incorporation and Immune-Modulating Agents

2026-07-16

Abstract excerpt

<title>Abstract</title> <p>Human papillomavirus (HPV)-associated malignancies remain a significant global health burden, particularly among individuals with established infection or limited access to prophylactic vaccination. Although the E6 and E7 oncogenes of high-risk HPV types represent attractive therapeutic targets, current vaccine approaches have shown limited clinical efficacy. In this study, we investiga...

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Literature Corpus work
1090370f-5b8d-515c-aae9-ed1a93de7043
DOI
10.21203/rs.3.rs-9890379/v1
Open publication

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Stepwise Enhancement of HPV16 E6/E7 mRNA Vaccine Efficacy Using HSV-1 gD Epitope Incorporation and Immune-Modulating AgentsDOI 10.21203/rs.3.rs-9890379/v1
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