Article
Unlocking the role of SH3PXD2B in epithelial-to-mesenchymal transition driving Breast Cancer Lung Metastasis
2024-10-18
Abstract excerpt
Despite advancements in breast cancer treatment, metastasis remains a significant challenge, contributing to high mortality rates. This study investigates the mechanisms underlying breast cancer lung metastasis, with a particular emphasis on the role of SH3PXD2B in driving epithelial-to-mesenchymal transition. Here, we analyzed RNA sequencing data from CCLE and TCGA databases and characterized that SH3PXD2B expres...
Topics
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- Adipokines, Inflammation, and Metabolic Diseases
- Cancer Cells and Metastasis
- Cancer-related molecular mechanisms research
- CRISPR and Genetic Engineering
- Genetics, Aging, and Longevity in Model Organisms
- Inflammatory Biomarkers in Disease Prognosis
- Microtubule and mitosis dynamics
- Telomeres, Telomerase, and Senescence
Identifiers and source
- Literature Corpus work
- fc3fc732-bbb8-5a7d-9366-c4d1834039e4
- DOI
- 10.1101/2024.10.16.618596
