Article

Low-dose apatinib and CPT synergistically optimize the tumor microenvironment and enhance the antitumor effects of PD-1 inhibitors in hepatocellular carcinoma

2023-11-20

Abstract excerpt

<h4>Background: </h4> Apatinib is a selective vascular endothelial growth factor receptor 2-tyrosine kinase inhibitor (TKI) that has been shown to apply to a variety of solid tumors, including advanced hepatocellular carcinoma(HCC). Clinical outcome prove that the combination of apatinib and anti programmed death 1 (PD-1) inhibitors has a cooperate with anti-tumor effect. In this study, we investigated the synergi...

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Literature Corpus work: fc345cf9-19c6-5140-b184-1016ecb8a698
DOI: 10.21203/rs.3.rs-3617675/v1

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