Article

A study on the anti-tumor effect and mechanism of arsenic trioxide on lung adenocarcinoma

2025-10-25

Abstract excerpt

<title>Abstract</title> <p>Background Lung adenocarcinoma is a common malignancy that urgently requires novel pharmacological interventions. Arsenic trioxide (ATO) has demonstrated antitumor activity in various cancers, but its mechanisms of action in lung adenocarcinoma cells remain unclear. Methods The 24-hour half-maximal inhibitory concentration (IC50) of ATO on human lung adenocarcinoma A549 cells was determ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f77886d2-aed9-58b9-9103-d66b5ea61bd4
DOI: 10.21203/rs.3.rs-7811550/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A study on the anti-tumor effect and mechanism of arsenic trioxide on lung adenocarcinomaDOI 10.21203/rs.3.rs-7811550/v1Read

Combination of Arsenic trioxide and Apatinib Synergistically Inhibits Small Cell Lung Cancer by Down-Regulating VEGFR2/mTOR and Akt/c-Myc Signaling Pathway via GRB10Semantic proximity Read

Combination of arsenic trioxide and apatinib synergistically inhibits small cell lung cancer by down-regulating VEGFR2/mTOR and Akt/c-Myc signaling pathway via GRB10Semantic proximity Read

Sodium Arsenite Induces Bronchial Epithelial Cell Cancer With Mitochondrial Dysfunction by Affecting Cell CycleSemantic proximity Read

Molecular Targets of Arsenic Trioxide in Malignant CellsSemantic proximity Read

Transcriptomic analysis on the effects of melatonin in gastrointestinal carcinomasSemantic proximity Read

Targeting mutant p53 with arsenic trioxide: A preclinical study focusing on triple negative breast cancerSemantic proximity Read

ITRAQ-Based Proteomics Analysis of Triptolide On Human A549 Lung Adenocarcinoma CellsSemantic proximity Read

Ailanthone inhibits non-small cell lung cancer cell growth through repressing DNA replication via downregulating RPA1Semantic proximity Read

YAP Manipulates Proliferation Via PTEN/AKT/mTOR-mediated Autophagy in Lung AdenocarcinomasSemantic proximity Read

The genomic landscape of sensitivity to arsenic trioxide uncovered by genome-wide CRISPR-Cas9 screeningSemantic proximity Read

Connections between endoplasmic reticulum stress-associated unfolded protein response, mitochondria, and autophagy in arsenic-induced carcinogenesisSemantic proximity Read

Lico A Causes ER Stress and Apoptosis via Up-Regulating miR-144-3p in Human Lung Cancer Cell Line H292Semantic proximity Read